The effect of intake of milk beverage in the morning on biological rhythm in human -focus on social jetlag and chronotype-

The effect of intake of milk beverage in the morning on biological rhythm in human -focus on social jetlag and chronotype- - The effect of intake of milk beverage in the morning on biological rhythm in human

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000026462

Enrollment

Registered

2017-03-09

Start date

2017-03-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Placebo group Intervention period (The period of beverage ingestion): 6 days Milk beverage in the morning Intervention period (The period of beverage ingestion): 6 days

Eligibility

Sex/Gender

Male

Inclusion criteria

Inclusion criteria: To be able to collect to hair follicle cells

Exclusion criteria

Exclusion criteria: 1) Milk allergy 2) To take medicine related to psychotropic, sleeping, steroid 3) Obesity (BMI>35kg/m2) and sleep apnea syndrome 4) High blood pressure (SBP:above140mmHg, and DBP:above 90mmHg) 5) To take medicine related to diabetes and hyperlipidemia 6) The principal investigator or the principal doctor judge the subject as inappropriate

Design outcomes

Primary

Measure	Time frame
PER3 *We will assess PER3 expression at baseline and post-intervention.	—

Secondary

Measure	Time frame
*We will assess below parameters at baseline and post-intervention. Hair follicle cell: NR1D1,NR1D2,CLOCK,PER1, PER2, CRY1, CRY2, BMAL1, BMAL2 Saliva:melatonin, testosterone, cortisol, chromogranin A, alpha-amylase, immunoglobulin A Assessment of physical activity and sleep: accelerometer, motionwatch, morningness-eveningness questionnaire, the center for epidemiologic studies depression scale, pittsburgh sleep quality index	—

Measure

Time frame

*We will assess below parameters at baseline and post-intervention. Hair follicle cell: NR1D1,NR1D2,CLOCK,PER1, PER2, CRY1, CRY2, BMAL1, BMAL2 Saliva:melatonin, testosterone, cortisol, chromogranin A, alpha-amylase, immunoglobulin A Assessment of physical activity and sleep: accelerometer, motionwatch, morningness-eveningness questionnaire, the center for epidemiologic studies depression scale, pittsburgh sleep quality index

—

Countries

Japan

Contacts

Public ContactMasaki Takahashi

Waseda University Comprehensive Research Organization

takahashi.m.bp@m.titech.ac.jp+81-3-5369-7318

Outcome results