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Development and clinical application of treatment for seasonal allergic rhinitis symptom caused by salivary secretory type IgA production.

Development and clinical application of treatment for seasonal allergic rhinitis symptom caused by salivary secretory type IgA production. - Development of mouthpiece for seasonal allergic rhinitis symptom

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000026428
Enrollment
50
Registered
2017-03-06
Start date
2017-03-07
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Seasonal allergic rhinitis

Interventions

The mouthpiece is set during the onset of allergic rhinitis symptoms (sneezing, runny nose, stuffy nose). Normal subjects who did not develop pollen symptoms were used as a control group.

Sponsors

Department of Oral Integrated Medicine Kanagawa Dental University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Hospitalized patients with symptoms of allergic rhinitis (house dust, PM 2.5 etc) visit our Kanagawa Dental hospital.

Exclusion criteria

Exclusion criteria: 1) Those who are undergoing treatment due to infection with hemophilia, hepatitis, HIV, etc, and who are at risk of treatment due to high blood pressure, diabetes etc. 2) Pregnant women or lactating women 3) Person who has participated in the trial within 12 weeks before the start of this procedure 4) Person who judged that the dental clinic in charge is not appropriate for other reasons

Design outcomes

Primary

MeasureTime frame
Evaluate relief of allergic rhinitis symptoms before and after mouthpiece attachment by allergic rhinitis severity classification.

Secondary

MeasureTime frame
Furthermore, changes in salivary secretion rate, salivary IgA concentration, salivary IL-33 concentration, and saliva properties are evaluated.

Countries

Japan

Contacts

Public ContactNobuyuki Tani-Ishii

Department of Oral Integrated Medicine ,Kanagawa Dental University Division of Pulp Biology

n.ishii@kdu.ac.jp0468229527

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026