The retrospective clinical study on inhibitory effect of 0.1% brimonidine ophthalmic solution against the optic disc hemorrhage

The retrospective clinical study on inhibitory effect of 0.1% brimonidine ophthalmic solution against the optic disc hemorrhage - Inhibitory effect of 0.1% brimonidine ophthalmic solution against the optic disc hemorrhage

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000026406

Enrollment

Registered

2017-03-15

Start date

2015-12-25

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Glaucoma

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1)Patients being treated for more than two years. 2)Patients administered with additional brimonidine for more than one year. 3)Patients with optic disc hemorrhage before administration of additional brimonidine. 4)Patients who had no addition or change with glaucoma therapeutic drugs except for addition of brimonidine addition and the end date of observation period. (If both eyes constitute indication, worse eye is chosen.)

Exclusion criteria

Exclusion criteria: 1)Patients with retinal disease. 2)Patients with corneal opacity. 3)Patients who underwent LASIK surgery. 4)Patients that cannot be enforced with accurate visual field tests. 5)Patients with MD value -25dB or below.

Design outcomes

Primary

Measure	Time frame
Comparison with the frequency of DH before and after addition of 0.1% brimonidine.	—

Secondary

Measure	Time frame
1) Ratio of frequency of DH occurrence 2) Intraocular pressure with Goldmann applanation tonometer	—

Countries

Japan

Contacts

Public ContactKoji Nitta

Fukui-ken Saiseikai Hospital Ophthalmology

nitta.koji7001@fukui.saiseikai.or.jp0776-23-1111

Outcome results