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Effectiveness of postoperative pain control with intravenous acetaminophen (Acelio) following esophageal cancer surgery: A prospective randomize controlled trial

Effectiveness of postoperative pain control with intravenous acetaminophen (Acelio) following esophageal cancer surgery: A prospective randomize controlled trial - Effectiveness of postoperative pain control with intravenous acetaminophen (Acelio) following esophageal cancer surgery: A prospective randomize controlled trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000026381
Enrollment
60
Registered
2017-04-01
Start date
2017-04-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Esophageal cancer

Interventions

The group with intravenous acetaminofen administration around the clock The group without intravenous acetaminofen administration

Sponsors

Tokushima university and graduated school
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: The patients planed to recieve thoracoscope assisted esophagectomy and hand assisted laparoscopic gastric tube reconstruction and 2 or 3 fields lymphoadenectomy. Maintain major organ function Got an informed consent

Exclusion criteria

Exclusion criteria: Open thoracotomy or open laparotpmy case One or more wound size over 10 cm in cervial ,thoracic, or abdominal incision. With major organ disfunction.

Design outcomes

Primary

MeasureTime frame
Reduce of additional dosage of epidual anesthesia by patient control pump and dosage of NSAIDs as rescue drug.

Secondary

MeasureTime frame
Reduce complaint related to opioid,reduce pain, the time of first gait, flatus, constipation,and hospital stay

Countries

Japan

Contacts

Public ContactTakeshi Nishino

Tokushima university and graduated school Thoracic, endocrine oncology and surgery

nishinotakeshi@tokushima-u.ac.jp088-633-7173

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026