Relation between intraluminal intensity of blood speckle on intravascular ultrasound and fractional flow reserve

Relation between intraluminal intensity of blood speckle on intravascular ultrasound and fractional flow reserve - Relation between intraluminal intensity of blood speckle on intravascular ultrasound and fractional flow reserve

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000026325

Enrollment

Registered

2017-03-01

Start date

2017-03-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary artery disease

Interventions

IVUS data acquisition and FFR measurement during percutaneous coronary intervention (PCI).

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who scheduled to undergo PCI.

Exclusion criteria

Exclusion criteria: 1) Patients with hemodialysis 2) Patients who use nhaled drugs or theophylline products for bronchial asthma 3) Patients with left main trunk lelsion or stenosis >50% at the distal to the target lesion. 4) Patients with chronic total obstruction 5) Patients with severe heart failure (ejection fraction <30% or NYHA >class 3) 6) Patients with prior coronary artery bypass grafting

Design outcomes

Primary

Measure	Time frame
Comparison between the difference in intraluminal intensity of blood speckle (Delta IBS) and fractional flow reserve (FFR) with or without hyperemia.	—

Secondary

Measure	Time frame
1) Comparison between Delta IBS and instantaneous wave-free ratio (iFR) with or without hyperemia. 2) Diagnostic Accuracy of Delta IBS for physiological assessment of coronary artery stenosis by FFR with or without hyperemia. 3) Diagnostic Accuracy of Delta IBS for physiological assessment of coronary artery stenosis by iFR with or without hyperemia. 4) Diagnostic Accuracy of minimum lumen area (MLA) on intravascular ultrasound (IVUS) for physiological assessment of coronary artery stenosis.	—

Measure

Time frame

1) Comparison between Delta IBS and instantaneous wave-free ratio (iFR) with or without hyperemia. 2) Diagnostic Accuracy of Delta IBS for physiological assessment of coronary artery stenosis by FFR with or without hyperemia. 3) Diagnostic Accuracy of Delta IBS for physiological assessment of coronary artery stenosis by iFR with or without hyperemia. 4) Diagnostic Accuracy of minimum lumen area (MLA) on intravascular ultrasound (IVUS) for physiological assessment of coronary artery stenosis.

—

Countries

Japan

Contacts

Public ContactYuichi Saito

Chiba University Hospital Department of Cardiovascular Medicine

policemaccho@yahoo.co.jp043-222-7171

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026