The effect of Lumbricus rubellus for tinnitus control: randomized double-blind placebo-controlled clinical trial

The effect of Lumbricus rubellus for tinnitus control: randomized double-blind placebo-controlled clinical trial - The effect of Lumbricus rubellus for tinnitus control

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000026251

Enrollment

Registered

2017-03-01

Start date

2017-03-15

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bilateral tinnitus in patients with age-associated hearing loss

Interventions

Lumbricus rubellus 600mg per day, 4 weeks placebo 4 weeks

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Patients show age-related hearing loss 2) Patients have bilateral tinnitus

Exclusion criteria

Exclusion criteria: 1) Tinnitus derived from inner ear diseases (sudden hearing loss, acoustic tumor, acoustic trauma, otosclerosis) 2) unilateral tinnitus

Design outcomes

Primary

Measure	Time frame
Tinnitus Handicap Inventory (THI-25), 4 weeks after medication	—

Secondary

Measure	Time frame
1) Pure Tone Audiometry, Speech Audiometry 2) Pitch match test 3) GTT test(coagulation time,lysis time)	—

Countries

Japan

Contacts

Public ContactKeiji Matsuda

University of Miyazaki Department of Otorhinolaryngology, Head and Neck Surgery

kmatsuda@med.miyazaki-u.ac.jp0985-85-2966

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026