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Identification of the actual states of the occurrence of hepatocellular carcinoma in patients with type 2 diabetes.

Identification of the actual states of the occurrence of hepatocellular carcinoma in patients with type 2 diabetes. - the occurrence of hepatocellular carcinoma in type 2 diabetic patients.

Status
Unknown
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000026246
Enrollment
600
Registered
2017-02-21
Start date
2017-01-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 diabetes

Interventions

None listed

Sponsors

Kumamoto University
Lead Sponsor
Department of Gastroenterology, The University of Tokyo Hospital Department of Diabetes and Metabolic Diseases, The University of Tokyo Hospital
Collaborator

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Subjects with type 2 diabetes who has non-B or non-C hepatocellular cancer and were followed by specialists of diabetes for at least 5 years were enrolled in this study. Moreover, subjects with diabetes who were enrolled in the "Okanoue study designed from Ministry of Health, Labour and Welfare: The observational study of NASH for the clarification of clinical states, diagnostic procedure and novel therapeutics."

Exclusion criteria

Exclusion criteria: 1) Subjects who were diagnosed as hepatocellular carcinoma at the age of 25 or less. 2) Subjects who were diagnosed as chronic hepatitis B or chronic hepatitis C. 3) Subjects who were not sutbable to enroll the study by physician in charge.

Design outcomes

Primary

MeasureTime frame
Comparison of several data showed below between HCC-developed and HCC-undeveloped type 2 diabetic patients. 1) gender, age, BMI, abdominal circumference, maximum body weight, treatment of diabetes, hypertension and dislipidemia, history of alcohol 2) blood examination: number of Plates 3) Blood chemistry: Albumin, AST, ALT, T-bil, BUN, s-Cre, GGT, ALP, T-Chol, TG, HDL-C, UA, blood glucose level, HbA1c, glicoalbumin 4) coagulation: prothrombin time

Countries

Japan

Contacts

Public ContactTakeshi Matsumura

Kumamoto University Hospital Diabetes, Metabolism and Endocrinology

takeshim@gpo.kumamoto-u.ac.jp0963735169

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026