Dental caries
Conditions
Interventions
D-tagatose gum The weight of one gum tablet is 1.5 g, used three times after each meals, chew 2 tables to 1 time for 10 minutes
Xylitol gum The weight of one gum tablet is 1.5 g, used three times af
Sponsors
Department of oral and maxillofacial surgery, Faculty of Medicine, Kagawa University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) High dental caries active person by saliva buffering ability test or intraoral examination 2) Person who can agree with writing on participation of this exam
Exclusion criteria
Exclusion criteria: 1) Low dental caries active person by saliva buffering ability test or intraoral examination 2) Person who cannot agree on participation of this exam even through parents or assistant 3) Antibiotics or anticancer drug, patient who was receiving the same treatment during radiation therapy treatment or within 1 year 4) Those judged unsuitable as subjects 5) Can not bite 3 g (2 tables) of gum for more than 10 minutes 6) Use of removable dentures, use of orthodontic treatment equipment 7) Salivary gland disease, xerostomia, renal dysfunction, abnormal liver function 8) Children under 6 years of age
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| About 10 ml of saliva is collected before starting the gum test and collected one week later periodically until the fourth week. Dilute saliva is seeded on BHI and Mitis Salivarious Bacitracin Agar (MSB) agar plates and bacterial counts are measured. | — |
Secondary
| Measure | Time frame |
|---|---|
| Evaluate bacterial counts of Streptococcus mutans or Lactobacillus with Dentocult SM or Dentocult LB kit. | — |
Countries
Japan
Contacts
Public ContactTakaaki Ogawa
Faculty of Medicine, Kagawa University Department of oral and maxillofacial surgery
Outcome results
None listed