Peri-implantitis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Person who obtained written informed consent. 2.One study implant have at least 2 sites of probing pocket depth (PPD) greater than 5 mm with bleeding on probing (BOP) and more than 3 mm bone loss.
Exclusion criteria
Exclusion criteria: 1.Persons who had received non-surgical peri-implant therapy within the previous 3 months 2.Persons who had received surgical peri-implant therapy within the previous 6 months 3.Persons who had taken systemic antibiotics or anti-inflammatory drugs within 3 months before experiment 4.Acute periodontal burden on the study implant and the adjacent natural tooth 5.Smoker 6.Persons who had severe systemic diseases 7.Persons who are pregnant or suspected to be pregnant 8.Pacemaker or any other systemic conditions that might be affected by the Er: YAG laser treatment 9.Persons who are judged to be unqualified for this study subjects by investigators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The changes of LPS level before and after the decontamination of affected implant surface. | — |
Secondary
| Measure | Time frame |
|---|---|
| Probing pocket depth Bone level Bacterial counts in subgingival plaque Biomarker level in peri-implant crevicular fluid | — |
Countries
Japan
Contacts
Niigata University Medical & Dental Hospital