Prymary open angle glaucoma
Conditions
Interventions
None listed
Sponsors
Department of Ophthalmology and Micro-technology, Yokohama City University School of Medicine, Yokohama, Japan
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Japanese men or women with primary open angle glaucoma,20 years of age or older, inadequately controlled IOP despite treatment with 3 or 4 drugs, IOP of less than 35 mmHg, and IOP difference less than 2 mm Hg between any 2 eligibility visits. We fixedthe target IOP at 18 mm Hg in the early phase, 15 mmHg in the intermidiate phase, and 12mm Hg in the late phase, according to Anderson's classification. We defined inadequately controlled IOP as a failure to decrease the IOP to its target value under the existing medical therapy.
Exclusion criteria
Exclusion criteria: The exclusion criteria were as follows: presence of secondary, steroid-related, or traumatic glaucoma, and narrow angles that are defined as grade 2 or less according to the Shaffer classification, as assessed using gonioscopy. We also excluded patients who had undergone ocular surgeries, including cataract surgery within the previous year; retinal laser treatment, selective laser trabeculoplasty, glaucoma surgery, or Nd:YAG laser posterior capsulotomy within the previous 90 days; and eyelid surgery within the previous 120 days. Patients with a corrected visual acuity worse than 20/200 in either eye or with severe visual field defects were also excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intraocular pressure lowering effect at 12 months after treatment | — |
Countries
Japan
Contacts
Public ContactHiroshi Inazaki
Department of Ophthalmology and Micro-technology, Yokohama City University School of Medicine, Yokoh Ophthalmology
Outcome results
None listed