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Assessment of ocular blood flow alterations in response to intraocular pressure elevation with Laser speckle flowgraphy

Assessment of ocular blood flow alterations in response to intraocular pressure elevation with Laser speckle flowgraphy - Assessment of ocular blood flow alterations in response to intraocular pressure elevation

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000026202
Enrollment
20
Registered
2017-02-24
Start date
2017-03-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy volunteers

Interventions

To investigate the ocular blood flow alterations in response to intraocular pressure elevation on two different days.

Sponsors

Tohoku University Graduate School of Medicine, Department of Ophthalmology
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Healthy volunteers Normal findings in slit lamp and funduscopic examinations No history of ophthalmic or general disorders, prior ocular laser or incisional surgery in either eye, and the use of systemic or topical medication Obtain written-informed consent from the subjects.

Exclusion criteria

Exclusion criteria: A regular smoking habit High myopia Baseline intraocular pressure less than 22mmHg in both eyes History of topical medication allergy In pregnancy History of unconfortable for periocular compression History of ophthalmic or general disorders, prior ocular laser or incisional surgery in either eye, and the use of systemic or topical medication No written-informed consent from the subjects

Design outcomes

Primary

MeasureTime frame
Ocular blood flow ratio and coefficient of variation in the intraocular pressure elevation phase was calculated with reference to this baseline.

Countries

Japan

Contacts

Public ContactYukihiro Shiga

Tohoku University Graduate School of Medicine Department of Ophthalmology

y.shiga@oph.med.tohoku.ac.jp022-717-7294

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026