Comparative study to evaluate the preventive effect of moisturizing agent(heparinoid) for radiation dermatitis in head and neck cancer.

Comparative study to evaluate the preventive effect of moisturizing agent(heparinoid) for radiation dermatitis in head and neck cancer. - Comparative study to evaluate the preventive effect of moisturizing agent(heparinoid) for radiation dermatitis in head and neck cancer.

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000026190

Enrollment

190

Registered

2017-04-01

Start date

2017-05-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Head and neck cancer

Interventions

Applying hirudoid soft ointment to the irradiated field twice daily beginning on the first day of radiation therapy, continuing throughout treatments (about 6-7weeks). Observation

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1)head and neck cancer(oral cavity, pharynx, or larynx) and planned to receive over 50Gy radiotherapy 2)Lack of previous radiotherapy for head and neck field 3)More than 20 years old at the time of the agreement acquisition 4)Written informed consent to participate in this study

Exclusion criteria

Exclusion criteria: 1)Early glottis carcinoma (T1-2N0) 2)Planned use of cetuximab 3)inflammatory or connective tissue disorder of the skin 4)hemorrhagic disease 5)psychiatric disease or psychiatric symptom 6)ineligible status judged by attending doctor

Design outcomes

Primary

Measure	Time frame
Incidence rate of radiation dermatitis over Grade 2(CTCAE ver. 4.0)	—

Secondary

Measure	Time frame
1)The time to incidence of radiation dermatitis over Grade 2 2)The highest grade of radiation dermatitis during observation period 3)Time course of QOL about skin symptom	—

Countries

Japan

Contacts

Public ContactMio Kojima

Tokyo medical and dental university Department of radiation oncology

kjmmrad@tmd.ac.jp03-3813-5311

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026