Effect of Personalized Dialysate Sodium Prescription on Plasma Sodium Concentration and Sodium Setpoint in Conventional, Quotidian and Nocturnal Hemodialysis.

Effect of Personalized Dialysate Sodium Prescription on Plasma Sodium Concentration and Sodium Setpoint in Conventional, Quotidian and Nocturnal Hemodialysis. - Personalized Dialysate Sodium concentration and effect on sodium setpoint and clinical outcomes in Home Hemodialysis patients.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000026102

Enrollment

Registered

2017-02-12

Start date

2013-07-15

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hemodialysis

Interventions

Intervention 1 = Personalized dialysate sodium set to 3 mmol/L above patient plasma pre-dialysis sodium setpoint. Intervention 2 = Personalized dialysate sodium set to 3 mmol/L below patient plasma pr

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: All patients in the home hemodialysis program of the Southwestern Ontario Regional Renal Program.

Exclusion criteria

Exclusion criteria: Age under 18, pregnancy, not expected to survive 6 months.

Design outcomes

Primary

Measure	Time frame
1. Interdialytic weight gain	—

Secondary

Measure	Time frame
1. Pre- and post-dialysis systolic and diastolic blood pressure. 2. Change in blood pressure (systolic and diastolic) during hemodialysis 3. Change in pre-dialysis patient plasma sodium setpoint.	—

Countries

North America

Contacts

Public ContactDr. Benjamin Thomson

Queen's University Nephrology

thomsonb@kgh.kari.net6135496666

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026