PAIN control after laparoscopic Surgery using EpiduRal anesthesia Versus Intravenous aCEtaminophen: an open-label pilot study

PAIN control after laparoscopic Surgery using EpiduRal anesthesia Versus Intravenous aCEtaminophen: an open-label pilot study - PAIN SERVICE pilot trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000026025

Enrollment

Registered

2017-02-08

Start date

2017-01-16

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients undergoing laparoscopic surgery

Interventions

Acelio Intravenous Injection 1000mg Epidural anesthesia

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1)Patients undergoing laparoscopic surgery i)gastrectomy ii)colorectal surgery iii)hepato-biliary-pancreatic(HBP) surgery 2)The age of patients >= 20 years

Exclusion criteria

Exclusion criteria: 1)Epidural catheter can not to be inserted technically 2)Platelet counts <= 100,000 3)Bleeding tendency 4)Patients who can not express their pain (can not use patient-controlled anesthesia) 5)Patients with severe comorbidity(heart failure, renal failure, psychiatric disorder and so on) 6)Transaminase(AST, ALT) >= twofold more than normal limits 7)Patients who took another oral analgesic within preoperative 8 hours 8)Pregnancy or breast-feeding women 9)Aspirin-induced asthma 10)Patient with allergy to acetaminophen, opioid or local anesthesia 11)Others

Design outcomes

Primary

Measure	Time frame
The amount of patient-controlled anesthesia for breakthrough analgesia at postoperative 72 hours	—

Secondary

Measure	Time frame
VAS(visual analogue scale) adverse effect	—

Countries

Japan

Contacts

Public ContactShinya Hayami

Wakayama Medical University 2nd Department of Surgery

shin-8@wakayama-med.ac.jp073-441-0613

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026