Investigation the effect of imprpving on postprandial blood glucose with type 2 diabetic patients by the combination of bran ingestion and alpha glucosidase inhibitor

Investigation the effect of imprpving on postprandial blood glucose with type 2 diabetic patients by the combination of bran ingestion and alpha glucosidase inhibitor - the effect of improving on postprandial blood glucose by the combination of bran ingestion and alpha glucosidase inhibitor

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000025998

Enrollment

Registered

2017-02-04

Start date

2014-03-30

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

type 2 diabetes

Interventions

Ingestion of unpolished rice bran before meals Combined administration of brown rice bran and pre-meal alpha glucosidase inhibitor No meals before administration

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients whose age is over 20 years old but less than 75 years old when acquiring consent 2. After receiving sufficient explanation for the participation of this study, patients who obtained document consent by the patient's free will with sufficient understanding 3. Patient in hospital 4. Patients whose blood glucose level is not more than 140 mg / dL on an empty stomach and below 200 mg / dL for 2 hours after a meal

Exclusion criteria

Exclusion criteria: 1. Type 1 diabetic patients 2. Patients who have used alpha GI and GLP 1 analog preparations so far 3. Patients using alpha glucosidase inhibitor and GLP-1 analog preparations 4. Women who may be pregnant or may become pregnant 5. Women who are breastfeeding 6. Women in menstruation during the study period 7. Patients determined by the attending physician to be unsuitable for this study

Design outcomes

Primary

Measure	Time frame
1 Mean blood glucose of 24 hours 2 MAGE (average value of differences in blood glucose level when blood glucose fluctuation exceeding average + 1SD) 3 total area of blood glucose fluctuation in 24 hours 4 Percentage of time zone of hyperglycemia (> 140 mg / dL) 5 Percentage of time zone of hypoglycemia (<70 mg / dL)	—

Countries

Japan

Contacts

Public ContactTaiga Nakayama

St. Marianna University School of Medicine Metabolism and Endocrinology

t2nakayama@marianna-u.ac.jp044-977-8111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026