A study on the detection of circulating tumor cells (CTCs) in patients with hepatocellular carcinoma and its clinical significance

A study on the detection of circulating tumor cells (CTCs) in patients with hepatocellular carcinoma and its clinical significance - CTC detection in HCC patients

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000025989

Enrollment

100

Registered

2017-02-03

Start date

2015-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hepatocellular carcinoma

Interventions

Peripheral, portal and hepatic vein blood samples will be drawn from HCC patients during surgery and will be tested for CTC enumeration.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Patients who are going to undergo hepatectomy for HCC 2) Patients who personally have given informed consent in writing

Exclusion criteria

Exclusion criteria: 1) History of active double cancer 2) Patients likely to be unable to personally give written informed consent and any other condition that the investigator feels would be inadequate for the safe conduct of this study

Design outcomes

Primary

Measure	Time frame
Glypican-3 positive CTC positivity rate for HCC patients	—

Secondary

Measure	Time frame
Relationship of the CTC positivity rate with postoperative recurrence and prognosis	—

Countries

Japan

Contacts

Public ContactTsuyoshi Kobayashi

Hirohshima university Department of Gastroenterological and Transplant Surgery

tsukoba@hiroshima-u.ac.jp082-257-5220

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026