N/A (healthy adults)
Conditions
Interventions
Oral intake of the test food (112 mL) twice a day for 4 weeks. Washout period for 3 weeks. Oral intake of the placebo (112mL) twice a day for 4 weeks.
Oral intake of the placebo (112 mL) twice a d
Sponsors
Center for Health Science Innovation, Osaka City University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: [1]Individuals whose written informed consent has been obtained. [2]Healthy adults aged 30-59 years.
Exclusion criteria
Exclusion criteria: [1]Individuals under medication or using medial products. [2]Individuals who have medical history of circulatory system diseases. [3]Individuals who have autonomic nervous system disorders. [4]Individuals who have medical history of neurological diseases such as unconsciousness, coma, convulsion, etc. [5]Individuals who have sleep disorders. [6]Individuals who have serious diseases such as diabetes, liver diseases, renal diseases, heart diseases. [7]Individuals who have serious pollinosis. [8]Individuals who are sensitive to foods or intolerant to lactose. [9]Individuals who excessively take alcohol(expressed in amount of alcohol: over 60 g/day) [10]Smokers. [11]Individuals who have a habit to take fermented milk or lactic acid bacteria beverage two days a week or more in the past 3 months. [12]Individuals who work the night shift. [13]Individuals whose BMI is not 17.0-30.9. [14]Individuals who have meal restrictions. [15]Women who are pregnant, breastfeeding, or wish to be pregnant in this study period. [16]Individuals who participated in other clinical trials in the past 1 month or are going to participate in other trials in this study period. [17]Individuals who are judged not suitable to participate in this trial by investigators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| [1]Autonomic nerve function [2]Cognitive function [3]Subjective Fatigue | — |
Secondary
| Measure | Time frame |
|---|---|
| [1]Condition of sleep [2]Physical active mass [3]Fatigue biomarker in blood | — |
Countries
Japan
Contacts
Public ContactMika Furusawa
Osaka City University Center for Health Science Innovation
Outcome results
None listed