The relationship between glycemic variability and baroreflex sensitivity in type 2 diabetic patients

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000025964

Enrollment

Registered

2017-02-28

Start date

2017-02-28

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 diabetes

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: ?Hospitalized type 2 diabetic patients ?Patients with HbA1c>6.0% and <10.0%

Exclusion criteria

Exclusion criteria: ?having arrhythmia ?receiving non-dihydropyridine calcium channel blockers ?receiving digitalis ?receiving antipsychotics ?having severe renal dysfunction (serum Cr > 2.5 mg/dl) ?having severe liver dysfunction (3 X the upper limit of normal) ?having severe infection, severe trauma, or pre and post operation ?having diabetic ketosis, diabetic coma, or insulin-dependent diabetes mellitus ?being pregnant ?having malignancy ?being unsuitable for participation in the trial for any reason, according to the investigators ?having myocardial infarction, heart failure or cerebral infarction within a half year ?heavy drinker

Design outcomes

Primary

Measure	Time frame
Coefficient of variation for glycemic variability and baroreflex sensitivity	—

Secondary

Measure	Time frame
?Standard deviation for glycemic variability and baroreflex sensitivity ?Mean amplitude of glycemic excursions for glycemic variability and baroreflex sensitivity ?Fasting plasma glucose and baroreflex sensitivity ?HbA1c and baroreflex sensitivity ?Intima media thickness of the carotid artery and baroreflex sensitivity ?Flow mediated dilation and baroreflex sensitivity	—

Countries

Japan

Outcome results