Seasonal allergic rhinitis
Conditions
Interventions
None listed
Sponsors
Ito ENT Clinic
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients who meet all of the following criteria at the visit1: (1) Patients who have been diagnosed over 2 years ago with allergic rhinitis to Japanese cedar or other pollens (2) Patients aged 20 or older and younger than 80 years (3) Patients with a T4NSS (sneezing, rhinorrhoea, nasal congestion, nasal itching) of 8 or more remaining after at least 2 weeks of taking non-tricyclic structural second generation antihistamic drug, where there is a plan to switch to tricyclic structural antihistamic drug (4) Patients who can provide written consent for participation in this study themselves and of their own free will with sufficient understanding after receiving sufficient explanation (5) Patients without communication problems
Exclusion criteria
Exclusion criteria: Patients who meet the following conditions (at Visit 1) are not selected as subjects: (1) Patients who have been treated with allergen immunotherapy (2) Patients with abnormal nasal cavity morphology such as nasal polyps or deviated nasal septum (3) Patients with severe liver or kidney dysfunction (4) Patients who are pregnant, breastfeeding, or desire pregnancy during the study period (5) In addition, patients who are judged to be inappropriate as subjects by the researcher
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in T4NSS (sneezing, rhinorrhoea, nasal congestion, nasal itching) from week 0 (Visit 1) to week 4 (Visit 3) | — |
Secondary
| Measure | Time frame |
|---|---|
| (1) Symptoms, QOL - T4NSS sub-score: score at each visit - Score of JRQLQ No.1 items I & II - Overall condition: face scale of JRQLQ No.1 items III (2) Treatment satisfaction - Treatment satisfaction percentage in questionnaire Other evaluation (3) Adverse events | — |
Countries
Japan
Contacts
Public ContactNobuhide Mori
Mebix, Inc. Research Promotion Group
Outcome results
None listed