Feasibility and safety of fentanyl with acetaminophen for pain control after liver resection

Feasibility and safety of fentanyl with acetaminophen for pain control after liver resection - Feasibility and safety of fentanyl with acetaminophen for pain control after liver resection

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000025894

Enrollment

Registered

2017-01-30

Start date

2017-02-10

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

liver disease (HCC, liver meta, ICC, living donor stc)

Interventions

prospective cohort Fentanyl with acetoaminophen 1.Fentanyl(continuous):0.5microg/kg/hr(POD0-3) 2.Acetoaminophen (every 6hours) :15mg/kg/every 6 hours(POD0-3)

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1.patient with liver function as Child-Pugh Grade A 2.Age over 20 years old 3.gender: free 4.Admission 5.Patients obtained informed concent

Exclusion criteria

Exclusion criteria: 1. Inappropriate patient for this research 2. patient with local inflammation in the injection site 3. sepsis 4. central nerve disorder 5. spinal cord disorder 6. contraindication for muscle relaxant agent 7. patient with respiratory disorder 8. convulsive seizure 9. asthma 10. sever liver dysfunction 11. gastric or duodenal ulcer 12. severe blood disease 13. severe renal dysfunction 14. sever heart failure 15. aspirin asthma 16. hypersensitivity for fentanyl or acetoaminophen

Design outcomes

Primary

Measure	Time frame
Blood oncentration of Acetoaminophen Liver dysfunction after liver resection Complications	—

Secondary

Measure	Time frame
Assessment of pain Dose of drug	—

Countries

Japan

Contacts

Public ContactMasaaki HIDAKA

Nagasaki University Hospital Department of Surgery

mahidaka@nagasaki-u.ac.jp095-819-7316

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026