Colorectal cancer
Conditions
Interventions
To take 1L of Asc-PEG + 0.5L of water the day before surgery
To take 2L of PEG-ELS the day before surgery
Sponsors
Hokkaido University Graduate School of Medicine, Gastroenterologial Surgery I
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patiens with colorectal cancer who are going to undergo laparoscopic surgery 2. Adenocarcinoma 3. Resectable primary lesion 4. Operative general condition 5. Age between 20 and 85 6. ECOG Performance Status between 0 and 2 7. Adequate informed consent
Exclusion criteria
Exclusion criteria: 1. Obstruction of gastrointestinal tract 2. Perforation of gastrointestinal tract 3. Discharge deficiency of stomach 4. Toxic megacolon 5. Deficiency of G-6-PD 6. Renal failure 7. Severe inflammatory bowel disease 8. Bowel stenosis 9. Disorder of vomiting reflux 10. Dehydration 11. Severe heart or liver disease 12. Anemia owing to tumor bleeding 13. Double cancer 14. Total parenteral nutrition 15. Preoeprative treatment (chemotherapy, radiotherapy, immunothrapy) 16. Uncontrollable diabetes mellitus 17. Severe lung disease 18. Drug allergy 19. Pregnancy 20. Unfitness judged by doctors
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The availability of bowel irrigation effect confirmed by laparoscope | — |
Secondary
| Measure | Time frame |
|---|---|
| a. Dilatation of small and large bowel b. Duration of bowel preparation c. Duration between the begin of taking Asc-PEG/PEG-ELS and the first evacuation d. Dose of Asc-PEG/PEG-ELS e. Patients' acceptability f. Recover of bowel movement g. Recover of patients' activity h. Conversion rate to open surgery i. Safety j. Postoperative inflammation response k. Differential analysis (tumor location, clinical classification, PS, age, gender,condition of evacuation, condition of taking Asc-PEG/PEG-ELS) | — |
Countries
Japan
Contacts
Public ContactShigenori Homma
Hokkaido University Hospital Gastroenterological Surgery I
Outcome results
None listed