Effects of monthly injected ibandronate on bone mineral density and microstructure in patients with primary osteoporosis after teriparatide treatment.

Effects of monthly injected ibandronate on bone mineral density and microstructure in patients with primary osteoporosis after teriparatide treatment. - Effects of injected ibandronate with primary osteoporosis after teriparatide treatment. MONUMENT Study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000025799

Enrollment

Registered

2017-01-26

Start date

2017-02-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Primary osteoporosis

Interventions

monthly injected ibandronate

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1 Primary osteoporosis patients received teriparatide 12months or more. 2 The patients who are able to receive ivandronate within 8weeks from teriparatide treatments. 3 Age:55 years and over 4 Gender:female 5 Out patients 6 Patients who agree with the documents.

Exclusion criteria

Exclusion criteria: 1 Patients with a history of critical heart disease, hepatic disease, kidney disease, diabetes mellitus, cancer, endcrine disease, metabolic disease, and secondary osteoporosis. 2 Patients taking steroids more than 5mg, and drugs affecting bone metabolism. 3 Patients with a history of allergy to ibandronate or bisphosphonate and hypocalcemia. 4 Patients with a history of Participation in clinical trials. 5 More than 3 vertebral fractures between L1 toL4. 6 Patients judged inappropriate by author.

Design outcomes

Primary

Measure	Time frame
Changing rates of bone mineral density from start to 12months after.	—

Secondary

Measure	Time frame
1)Changing rates of bone mineral density of lumbar from start to 6 months after. 2)Areal bone mineral density of femur and distal radius,Changing rates of SOS in Calcaneus,Incidences of vertebral fracture,Meaturemenst of Bone turnover markers,Changing rates of Visual Analog Scale,Microarchitectures of cotical bone and cancellous bone,Changing rates of predictive bone stiffness,Changinn rates of femur morphology.	—

Measure

Time frame

1)Changing rates of bone mineral density of lumbar from start to 6 months after. 2)Areal bone mineral density of femur and distal radius,Changing rates of SOS in Calcaneus,Incidences of vertebral fracture,Meaturemenst of Bone turnover markers,Changing rates of Visual Analog Scale,Microarchitectures of cotical bone and cancellous bone,Changing rates of predictive bone stiffness,Changinn rates of femur morphology.

—

Countries

Japan

Contacts

Public ContactKo Chiba

Nagasaki University Hospital Department of orthopaedic surgery

kohchiba@estate.ocn.ne.jp095-819-7321

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026