The effects on two conventional medication, acetaminophen and loxoprofen, for musculoskeletal pain including neck pain, low back pain, and knee pain. -multicenter longitudinal study -

The effects on two conventional medication, acetaminophen and loxoprofen, for musculoskeletal pain including neck pain, low back pain, and knee pain. -multicenter longitudinal study - - The effects on two conventional medication for musculoskeletal pain

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000025797

Enrollment

310

Registered

2017-01-23

Start date

2015-04-09

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Musculoskeletal pain

Interventions

Oral administration of loxoprofen 60 mg/time, three times a day, for 1 month. Oral administration of Acetaminophen 600 mg/time, four times a day, for 1 month

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1)The subjects who complain of following musculoskeletal pain; neck pain, low back pain, and knee pain, within four weeks after the onset of an acute pain episode. 2)The subjects are in-patients clinic or out-patients clinic. 3)The subjects who can agree to participate in this study.

Exclusion criteria

Exclusion criteria: 1)The subjects just seek second opinion. 2)History of malignant disease. 3)The subjects with surgical histories within six month. 4)The subjects considered inappropriate by the attending doctor.

Design outcomes

Primary

Measure	Time frame
Bio-equivalence of the effects on two conventional medications for pain reduction in musculoskeletal pain.	—

Secondary

Measure	Time frame
Pain Disability Assessment Scale, Hospital Anxiety and Depression Scale, Pain Catastrophizing Scale, Work Productivity and Activity Impairment, Euro-QOL 5 Dimension, Adverse effect, Laboratory examination.	—

Countries

Japan

Contacts

Public ContactKenji Miki

Osaka University Department of Pain Medicine

kenkyu@pain.med.osaka-u.ac.jp06-6879-3745

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026