Clinical research paper carried out on healthy subjects not suffering from skin diseases
Conditions
Interventions
None listed
Sponsors
Adaptgen Pharmaceutical Co., Ltd.
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: [PICOS] (Patients) Clinical study conducted in Japan for persons not suffering from skin diseases (Interventions) 1. Ongoing intake of glucosylceramide containing supplements 2. Continuous intake of food containing glucosylceramide (Control) as a control composition (control group) 1. Supplements not containing glucosylceramide 2. Foods not containing glucosylceramide (Outcome) Continuous uptake of glucosylceramide improves skin moisturizing function (Example) 1. Evaluation by medical consultation, interview, palpation, visual inspection etc. 2. Measured values such as percutaneous water transpiration amount, horny layer water content (Study design) Placebo or non glucosylceramide as control 1. Double blind parallel group comparison test 2. Single blind parallel group comparison test 3. Double blind crossover comparative test 4. Single blind crossover comparison test Contains glucosylceramide 1. Dose setting test 2. Gradual increase / decrease test [Selection criteria (eligibility criteria)] In the primary screening, among the candidate literatures assumed to be clinical studies concerning the oral intake of plant-derived glucosiceramide targeted to Japanese conducted in Japan by the abstract of Medical Magazine WEB, the following selection criteria Criteria), one corresponding to one or more is taken as a temporary candidate document. 1. Clinical research literature for domestic non-affected persons with skin 2. Literature of clinical research for adults conducted in Japan 3. Clinical research literature extracted by medical magazine WEB of literature retrieval system 4. Clinical research literature conducted by public institutions 5. Clinical research literature published by National Institute of Research and Technology Agriculture Food Industry Research Organization (Agricultural Research Organization) 6. Clinical research literature adopted by the reviewer's agreement besides the medical magazine WEB
Exclusion criteria
Exclusion criteria: [Exclusion Criteria] In the secondary screening, provisional candidate documents are obtained by the abstract, and those corresponding to one or more of the following exclusion criteria are excluded from the candidate literature. 1. Clinical research literature for subjects suffering from skin diseases 2. Literature of clinical research for minors 3. Clinical research literature for pregnant women and lactating women 4. Clinical research literature not reviewed 5. Literature of clinical study without comparative control group 6. Literature of clinical study in which the main involved component is not glucosylceramide 7. Clinical research literature which can not be evaluated by glucosylceramide and other equivalent ingredients 8. In addition, clinical research literature judged inappropriate by the reviewer's agreement
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluate the influence of continuous ingestion of food-derived functional ingredient "glucosylceramide" on skin moisturizing | — |
Countries
Japan
Contacts
Public ContactToru Urakawa
Adaptgen Pharmaceutical Co., Ltd. Sales Planning Division & Clinical development division
Outcome results
None listed