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Biochemical analysis of tear composition in dry eye patients

Biochemical analysis of tear composition in dry eye patients - Biochemical analysis of tear composition

Status
Unknown
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000025752
Enrollment
100
Registered
2017-01-20
Start date
2010-07-07
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dry eye

Interventions

None listed

Sponsors

Department of Ophthalmology, National Hospital Organization Tokyo Medical Center
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Dry eye patients (defined by the diagnostic criteria of Japan dry eye society 2006)

Exclusion criteria

Exclusion criteria: 1) Complication of anterior disease(blepharitis, lagophthalmos, blepharospasm and iritis) other than dry eye ( patients with past history of the above disease are included). 2) Patients who were assessed as inadequate.

Design outcomes

Primary

MeasureTime frame
Tears are colloected by Schirmer test strips from the dry eye patints, which are clinically performed. After the elution of tear protein and lipid, total protein and lactoferrinm lipocalin, lysozyme and secretory IgA are measured. And cytokines, phospholipase A2, lipids are fractioned and quantified.

Countries

Japan

Contacts

Public ContactChika Shigeyasu

National Hospital Organization Tokyo Medical Center Division for Vision Research, National Institute of Sensory Organs

shigeyasu@kankakuki.go.jp03-3411-0379

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026