Cryo-preservation and auto-transplantation of ovarin tissues in primary ovarian insufficient patients.

Cryo-preservation and auto-transplantation of ovarin tissues in primary ovarian insufficient patients. - in vitro activaton of ovarian follicle

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000025735

Enrollment

150

Registered

2017-01-19

Start date

2017-02-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

primary ovarian insufficiency (POI)

Interventions

Excise ovary from the patients and freeze-thaw the ovary. Culture thawed ovarian fragments to activate follicles for 2 days and perform auto-transplantation. After grafting, follicle growth will be mo

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Individuals who have the ability to provide written informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients who can not obtain written informe consent. 2. Patients who exceed reproductive age at the time of auto-transplantation. (more than or equal to 47 years old.) 3. Patients judged to be inappropriate for the study by the physicians.

Design outcomes

Primary

Measure	Time frame
Safety and efficacy of the ovarian tissue cryo-preservation and thawing followed by auto-transplantation into patients to improve their quality of life and infertility.	—

Countries

Japan

Contacts

Public ContactMasami Ito

The University of Toyama Obstetrics and Gynecology

obgyn@med.u-toyama.ac.jp076-434-7357

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026