atopic dermatitis, psoriasis, Patient receiving EGFR inhibitor
Conditions
Sponsors
Hokkaido University Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: ?Patients with skin disorders such as atopic dermatitis, psoriasis or the like, or patients with dry symptoms of the skin by EGFR inhibitor administration ?Those who are judged to be expected to improve dry skin symptoms due to the use of this research item ?The treatment of the original disease is not restricted ?There is no problem in terms of age and gender (including children) ?After receiving sufficient explanation for participation in this research, after sufficient understanding, the patient himself (a substitute in the case of a minor, but the principal and the substitute person over the age of 16 is free) by the free will Patient who got written consent
Exclusion criteria
Exclusion criteria: ?Person who experienced skin symptoms such as contact dermatitis due to the ingredients of this research item and similar ingredients ?Persons who have skin lesions etc. that are inappropriate for the application of this research item at the application site ?Persons who can not be examined after 8 weeks (in principle) ?pregnancy and lactating ?In addition, patients who the research staff judged inappropriate as subjects
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement of skin dryness (skin findings) Drying scores before and after the test at each observation site have changed by 1 or more | — |
Secondary
| Measure | Time frame |
|---|---|
| Skin physiological verification (changes in skin measurement value and cytokine in epidermal horny layer) Changes in stratum corneum water content, epidermal water transpiration amount, IL-1a, TARC, TSLP Improvement of QOL and feeling of use of this research product by questionnaire Changes in the subscales (functions, symptoms, emotions, comprehensive) of Skindex - 16 which is a skin disease specific scale and feeling of use feeling (feeling of moisture, stickiness, etc.) of the questionnaire | — |
Countries
Japan
Contacts
Public ContactHiroaki Iwata
Hokkaido University Hospital Dermatology
Outcome results
None listed