Cerebral rSO2(regional saturation of oxygen) monitoring in cardiopulmonary arrest patients :non randomized prospective multicenter study

Cerebral rSO2(regional saturation of oxygen) monitoring in cardiopulmonary arrest patients :non randomized prospective multicenter study - Continuous Chest ComPression Resuscitation for 16 minutes: CCCPR16 study (tripleCPR16 study)

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000025684

Enrollment

225

Registered

2017-01-15

Start date

2017-01-17

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cardiopulmonary arrest patients on arrival at hospital

Interventions

Continuous chest compression for 16 minutes and/or until achievement of the target cerebral rSO2 values.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: The patients with asystole or PEA for the initial rhythm on arrival at hospital

Exclusion criteria

Exclusion criteria: The patients with Vf or pVT for the initial rhythm on arrival at hospital

Design outcomes

Primary

Measure	Time frame
Primary outcome: continuous chest compression results in the increase of return of spontaneous circulation.	—

Secondary

Measure	Time frame
Secondary outcome: Achievement of Target values of rSO2 under continuous chest compression is faster (10% increase in the group of more than 50% of initial mean rSO2 value, 20% increase in the group between 40 and 50 % of initial mean rSO2 value, 35% increase in the group less than 40% of initial rSO2 mean value) than conventional chest compression with 2 minutes interval rhythm check. Thirtiary outcome: Adverse effect is not expected due to continuous chest compression for 16 minutes.	—

Measure

Time frame

Secondary outcome: Achievement of Target values of rSO2 under continuous chest compression is faster (10% increase in the group of more than 50% of initial mean rSO2 value, 20% increase in the group between 40 and 50 % of initial mean rSO2 value, 35% increase in the group less than 40% of initial rSO2 mean value) than conventional chest compression with 2 minutes interval rhythm check. Thirtiary outcome: Adverse effect is not expected due to continuous chest compression for 16 minutes.

—

Countries

Japan

Contacts

Public ContactMitsuo Ohnishi

Osaka University Graduate School of Medicine Department of Traumatology and Acute Critical Medicine

mohnishi@hp-emerg.med.osaka-u.ac.jp06-6879-5707

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026