Cholinergic urticaria
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Three subtypes of cholinergic urticaria Patients with hyperrsensitivity to sweat with angioedema Patients with hyperrsensitivity to sweat without angioedema Patients with hyperrsensitivity to serum or with hypohidrosis 2.Provided written informed consent
Exclusion criteria
Exclusion criteria: 1.Contraindications of bronchial responsiveness test 2.Patients with uncontrolled asthma under the treatment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Minimum cumulative dose of methacholine (D min) required to increase airway resistance | — |
Secondary
| Measure | Time frame |
|---|---|
| Slope of respiratory conductance (S Crs/Grs cont) from the baseline Respiratory symptoms Fractional exhaled nitric oxide (FeNO) Lung function test | — |
Countries
Japan
Contacts
Kobe University Graduate School of Medicine Division of Respiratory Medicine, Department of Internal Medicine