Healthy adults
Conditions
Interventions
Apply the carbonate cosmetics and the designated lotion on facial skin for twice a day for 4 weeks
Apply the placebo cosmetics and the designated lotion on facial skin for twice a day for 4 weeks
App
Sponsors
Kao Corporation
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Healthy female aged from 35 to 45 years old. 2. Person who is concerned about their skin being rough, dry, wrinkling and dull. 3. Person whose skin state changes with body condition (example: stress, fatigue and lack of sleep) easily. 4. Person who can agree to participate in the study voluntarily in writing. 5. Person who can agree to change her currently-using cosmetics to designated ones during the test period.
Exclusion criteria
Exclusion criteria: 1. Person who has abnormalities in the skin of the measurement region 2. Person who regularly goes to hospital. 3. Person with the anamnesis of an alcohol or drug dependence. 4. Person who regularly use drug (hypnotic drug, anti-allergic drug, analgetic drug, hormonal drug, laxative, antiflatulent etc..). 5. Person who has possibilities for emerging allergy to cosmetics and/or foods (including experiences of skin irritation by cosmetics within a year). 6. Person who has allergy to adhesive tape and/or medical tape. 7. Person who suffers pollen allergy, rhinitis and atopic dermatitis. 8. Person who is pregnant or lactating, or planned to become pregnant during a test period. 9. Person who participates in the other clinical studies within 4 weeks in the past, or person who scheduled to participate in other clinical studies during the test period. 10. Person who is judged as unsuitable for the study by the investigator for other reasons. 11. Person who herself and/or her family member are working for the cosmetics company, the food company, an advertising agency, investigation and consultant business, and a mass media-related company. 12. Patient with vascular function disorder, or person who has excessive sensitivity to cold. 13. Person who has abnormal blood pressure or electrocardiogram testing result. 14. Current smoker. 15. Person who experienced medical cosmetic treatment (i.e. cosmetic surgery, collagen injection etc..)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluation of the stratum corneum water content, transepidermal water loss, sebum secretion, skin color, skin viscoelasticity, stratum corneum cell size and composition, blood flow measurement and dermatological assessment after repeated treatments for 4 weeks with the carbonate cosmetics | — |
Countries
Japan
Contacts
Public ContactYasuko Amano
Kao Corporation R&D Skin Care Products Research
Outcome results
None listed