Psychiatric disorders
Conditions
Interventions
Test material: Dried royal jelly powder Duration: 8 weeks Dose: Daily 1000mg (equivalent to 3000 mg of fresh Royal Jelly)
Test material: Placebo Duration: 8 weeks Dose: Casein 500mg, carbohydrate
Sponsors
Hokkaido University Department of Psychiatry
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Men and women aged 30 to 75 years old (2) BMI of more than 25
Exclusion criteria
Exclusion criteria: (1) Those who are being treated for psychiatric or neurological diseases (2) Those who are diagnosed metabolic syndrome and currently being treated (3) Those who currently have or previously had asthma (4) Those who currently have or previously had food allergies
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Survey 8 weeks after administration Electroencephalography (event-related potential P3a & P3b, mismatch negativity, evoked gamma rhythms, and auditory evoked potentials) | — |
Secondary
| Measure | Time frame |
|---|---|
| Questionnaires (BDI, PANAS) Evaluation of cognitive function (attention network test, word frequency test, digit symbol substitution test, verbal learning test, effort based decision making test) MRS (measurement of glutathione, NAA, NAAG, glutamate, glutamine) Biochemical analysis (sleep-wake cycle-related hormones, inflammatory factors, stress-related hormones) | — |
Countries
Japan
Contacts
Public ContactAtsuhito Toyomaki
Hokkaido University Graduate School of Medicine Department of Psychiatry
Outcome results
None listed