Comparisons of morphological measurement and intracoronary hemodynamic parameters between coronary computed tomography and optical coherence tomography

Comparisons of morphological measurement and intracoronary hemodynamic parameters between coronary computed tomography and optical coherence tomography - Comparisons of morphological measurement and intracoronary hemodynamic parameters between coronary computed tomography and optical coherence tomography

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000025612

Enrollment

150

Registered

2017-01-11

Start date

2008-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

coronary artery disease

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who underwent cCTA prior to coronary angiography and OCT within 6 months.

Exclusion criteria

Exclusion criteria: 1. Prior coronary artery bypass graft (CABG) surgery 2. Contraindication to beta blocker agents or nitrates 3. Tachycardia or significant arrhythmia 4. Impaired chronic renal function (eGFR <30) 5. Subjects with known anaphylactic allergy to iodinated contrast material 6. Pregnancy or unknown pregnancy status in subject of childbearing potential 7. Cases with poor OCT or CCTA image for analyzing

Design outcomes

Primary

Measure	Time frame
To evaluate the concordance between cCTA minimal lumen area (MLA) and OCT MLA.	—

Secondary

Measure	Time frame
To evaluate the concordance between FFR value which derived cCTA and OCT. To evaluate the relation between coronary plaque characteristics and hemodynamic parameters by OCT and cCTA.	—

Countries

Japan

Contacts

Public ContactKenzo Uzu

Kobe University Graduate School of Medicine Division of Cardiovascular Medicine

kenzouduu@hotmail.com+81-78-382-5846

Outcome results