Verification for the efficacy of third look endoscopy to prevent delayed postoperative bleeding after gastric endoscopic submucosal dissection in patients with antithrombotic drugs -a prospective study-

Verification for the efficacy of third look endoscopy to prevent delayed postoperative bleeding after gastric endoscopic submucosal dissection in patients with antithrombotic drugs -a prospective study- - Efficacy of third look endoscopy to prevent delayed bleeding after gastric ESD in patients with antithrombotic drugs

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000025607

Enrollment

100

Registered

2017-01-16

Start date

2017-01-16

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

early gastric cancer / adenoma

Interventions

To perform 3rd-look endoscopy 5days later after ESD

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1)patients with histological diagnosis as gastric adenocarcinoma or adenoma (2)patients without history of gastrectomy or esophagectomy (3)patients with antithrombotic agents regardless of drug withdrawal (4)PS(ECOG)0,1,2 (5) patients who can be followed up more than 28days after ESD (6)patients with written informed consent of this study

Exclusion criteria

Exclusion criteria: (1) Patient with severe infection (2) Patient who are pregnant, may be pregnant, or prefer pregnancy during treatment (3)for Mental disease, dementia,it is difficult to participate study (4) Patient with unstable angina, or myocardial infarction within 6 months. (5)Patient with respiratory diseases requiring continuous oxygen therapy (6)Patient with uncontrollable hypertension (7)Patient with uncontrollable Diabetes (8)anemia requiring transfusion(Hb<7.0g/dl), Easy to bleed for low platelet (Plt<50000) (9) Patient judged inappropriate

Design outcomes

Primary

Measure	Time frame
Overall delayed bleeding rate	—

Secondary

Measure	Time frame
the early phase delayed bleeding rate the late phase delayed bleeding rate the delayed bleeding rate compared with the historical control group using propensity score matching.	—

Countries

Japan

Contacts

Public ContactKingo hirasawa

Yokohama City University Medical Center Division of Endoscopy

ryosuke@yokohama-cu.ac.jp0452615656

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026