The effect of inhaled bronchodilators on surgery for lung cancer surgery in patients with chronic obstructive lung disease; multicenter study

The effect of inhaled bronchodilators on surgery for lung cancer surgery in patients with chronic obstructive lung disease; multicenter study - The effect of inhaled bronchodilators on surgery for lung cancer surgery in patients with chronic obstructive lung disease

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000025587

Enrollment

100

Registered

2017-01-10

Start date

2017-01-10

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Primary lung cancer

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Clinically suspected primaruy lung cancer 2. FEV1/FVC<0.7 assessed by spirometry 3. Resectable cancer lesion by surgery less than single lobectomy 4. Patients stopping smoking 1 month before case registration 5. Adequate organ function tolerable for the general anesthesia 6. Capable of inhalation 7. Age of 20years or older 8. ECOG performance status 0-1 9. Written informed consent to participate

Exclusion criteria

Exclusion criteria: 1. Previously treated for COPD or bronchial asthma 2. Patients with past pulmonary resection 3. History of active infection 4. Patients with psychiatric disease 5. Patients who are judged inappropriate to entry this study by physician

Design outcomes

Primary

Measure	Time frame
Rate of cardiopulmonary complications within 30 days after surgery	—

Secondary

Measure	Time frame
1) Improvement of pulmonary function before and after inhalation of bronchodilators 2) Rate of postoperative coplications exclusing cardiopulmonary complications 3) Pulmonary function 1 year after surgery 4) 5-year survival rate	—

Countries

Japan

Contacts

Public ContactYasushi Shintani

Osaka University Graduate School of Medicine General Thoracic Surgery

yshintani@thoracic.med.osaka-u.ac.jp0668793152

Outcome results