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Measurement of intracerebral drug concentration using magnetic resonance spectroscopy (MRS)

Measurement of intracerebral drug concentration using magnetic resonance spectroscopy (MRS) - Brain drug concentration measurement with MRS

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000025586
Enrollment
16
Registered
2017-01-10
Start date
2017-02-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

heanlth vonlunteers

Interventions

Following oral administration of acetoaminophen 300 mg, brain NMR signals are observed using MRS. Following oral administration of diphenhydramine 50 mg, brain NMR signals are observed using MRS.

Sponsors

Tohoku University Cyclotron and Radioisotope Center
Lead Sponsor
Advanced clinical research center, Fukushima prefectural Medical University
Collaborator

Eligibility

Sex/Gender
Male

Inclusion criteria

Inclusion criteria: 1

Exclusion criteria

Exclusion criteria: 1

Design outcomes

Primary

MeasureTime frame
peak information (Hz) of orally-administered drugs

Secondary

MeasureTime frame
subjective felleing of study participants

Countries

Japan

Contacts

Public ContactKazuko TAKEDA

Tohoku University Cyclotron and Radioisotope Center

clinic_supporter@cyric.tohoku.ac.jp022-795-4438

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026