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The examination of the effect of intranasal anti-histamine on intranasal corticosteroid in Japanese cedar pollinosis

The examination of the effect of intranasal anti-histamine on intranasal corticosteroid in Japanese cedar pollinosis - The examination of the effect of intranasal anti-histamine on intranasal corticosteroid in Japanese cedar pollinosis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000025508
Enrollment
40
Registered
2017-02-22
Start date
2017-02-22
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Japanese cedar pollinosis

Interventions

Group A:intranasal corticosteroid(100microgram,once a day) and intranasal anti-histamine(0.05mg, four times a day)(2 weeks:from March 1 to March 15) Group B:intranasal corticosteroid(100microgram, onc

Sponsors

Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Department of Otolaryngology-Head & Neck Surgery
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: The patients of Japanese cedar pollinosis(between the age of 16 and 65 years, for at least a 2-year history of Japanese cedar pollinosis)

Exclusion criteria

Exclusion criteria: 1)concomitant sinonasal disease that could potentially affect the outcome of the trial (e.g., rhinosinusitis with nasal polyps, nasal septum deviation) 2)concomitant treatment for AR caused by allergens other than Japanese cedar pollen 3)rhinitis medicamentosa and non-allergic rhinitis 4)medication with anti-allergic drugs including H1RA, chromones, glucocorticoids and decongestants within 2 weeks of study initiation 5)sinonasal surgery including laser vaporization of inferior turbinates within 1 year 6)hypersensitivity to intranasal corticosteroid or intranasal ant-histamine 7)systemic infection including mycosis 8)pregnancy and breastfeeding

Design outcomes

Primary

MeasureTime frame
Total nasal symptom score

Secondary

MeasureTime frame
Total ocular symptom score, total symptom score, and QOL score

Countries

Japan

Contacts

Public ContactTakenori Haruna

Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Department of Otolaryngology-Head & Neck Surgery

haruna-t@cc.okayama-u.ac.jp086-235-7307

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026