diabetes mellitus
Conditions
Interventions
switching from insulin glargine U100 to U300 in the same unit during 30 days
adjuasting insulin dose by using self-titration algorithm (3-3-1 algorithm) during 90 days
Sponsors
Fukuiken Saisekai Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1)patient with type 1 or 2 diabetes treated with once daily insulin glargin for moer than 12 weeks (2) HbA1c(NGSP) 7.0 - 11.0% (3) Patients who can continue self-monitoring of fasting blood glucose in early morning (4) Age, 20 - 50 year old (5) Patients who can agree to take part in this study
Exclusion criteria
Exclusion criteria: -Patients who do not consent to the study. -Patients who have had severe ketosis or who have been in a diabetic coma or precoma within the past 6 months. -Patients who have a severe infection, are in pre/post operation, or have a serious wound. -Patients who are pregnant, lactating or may become pregnant. -Patients judged by their primary physician that they are not appropriate to participate the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.Changes in mean value and standard deviation (SD)of fasting blood glucose in early morning 2.Changes in HbA1c and glycated albumin levels after self-titration algorithm (3-3-1 algorithm) | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Contributing factors on SD of fasting blood glucose in early morning 2. Change in patient feeling of use 3. Change in body weight,blood pressure and lipid profile 4.symptomatic or severe hypoglycemia 5. another adverse events and side effects | — |
Countries
Japan
Contacts
Public ContactKazuo Notsumata
Fukuiken Saisekai Hospital Internal medicine
Outcome results
None listed