Advanced Lung Cancer
Conditions
Interventions
Patients with advanced lung cancer undergoing first-line chemotherapy will receive interventions based on specialized palliative care comprehensive program. The program contains the promotion of the i
Sponsors
National Cancer Center
Japan Supportive, Palliative and Psychosocial Oncology Group
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Histlogically or cytologically proven lung cancer (2) Stage IV non-small cell lung cancer or extensive-disease small cell lung cancer (3)Negative or unknown status of gene mutations for which molecular-targeted therapy is applicable (e.g. EGFR, ALK, ROS1, or BRAF) (4)Scheduled for first-line chemotherapy (other than immunotherapy) (5)Absence of history of any previous anticancer treatment for lung cancer (including chemotherapy, surgery, radiation therapy with curative intent and/or immunotherapy) (6)Initial administration of the first line chemotherapy in inpatient hospital setting (7) Age >= 20 years (8) Written informed consent for participation in this study
Exclusion criteria
Exclusion criteria: (1) Already consulted outpatient palliative medicine clinic or outpatient psycho-oncology clinic before entry to this study, and scheduled to receive the medical care subsequently (2) Already received intervention of specialty palliative care service before entry to this study (3) With severe cognitive impairment (4) unable to comprehend Japanese (5) Already participate in other intervention studies which prohibit participation in this study. (6) Considered ineligible for this study by the physician in charge
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The change in the score on the Functional Assessment of Cancer Therapy-Lung Trial Outcome Index (FACT-L TOI) from baseline to 3 months | — |
Secondary
| Measure | Time frame |
|---|---|
| (1) FACT-L score (2) FACT-L Lung Cancer Subscale(LCS) score (3) Proportion of patients with depression assessed by Patient Health Questionnaire 9 (PHQ-9) (4) PHQ-9 score (5) Proportion of patients with anxiety assessed by generalized anxiety disorder 7-item (GAD-7) (6) GAD-7 score (7) EuroQol 5 Dimension (EQ-5D) score (8) Proportion of responses to each item in the questionnaire about illness understanding (9) Proportion of responses to each item in the questionnaire about medical services received (10) One-year survival rate (11) Overall survival (12) Visiting time with patients taken for each professions belonging to specialized palliative care service to meet with patients (13) Proportion of the place of death (14) Days from the last chemotherapy to death (15) Days of hospital stay in general wards during one month before death (16) Days of hospice usage during one month before death (17) Proportion of hospice usage during one month before death (18) Proportion of cardiopulmonary resuscitation | — |
Countries
Japan
Contacts
Public ContactYoshihisa Matsumoto
National Cancer Center Hospital East Department of Palliative Medicine
Outcome results
None listed