Efficacy of Kakkonto in oral immunotherapy for food Allergy : Randomized Controlled Trial

Efficacy of Kakkonto in oral immunotherapy for food Allergy : Randomized Controlled Trial - Efficacy of oral immunotherapy combinated Kakkonto

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000025470

Enrollment

Registered

2016-12-29

Start date

2016-12-26

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

food allergy

Interventions

Combination of anti-allergic drug and Kakkonto at introduction of oral immunotherapy for 5weeks Combination of anti-allergic drug at introduction of oral immunotherapy for 5weeks

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1.Food allergy diagnosised by oral food challenge without tendency of natural outgrow 2. Children who obtain the informed consent of the study 3. Those who can take medicine of kakkonto 4. Patients who have secured medical institutions in emergency

Exclusion criteria

Exclusion criteria: 1.Complication or past history of heart, liver and kidney diseases. 2.Uncontrolled asthma, atopic dermatitis, allergic rhinitis 3.Children who were judged as inappropriate by the study director

Design outcomes

Primary

Measure	Time frame
Efficacy of oral immunotherapy induced acute reactions and side reaction by Kakkonto	—

Secondary

Measure	Time frame
1.Change of dose threshold in oral food challenge after 24 weeks of treatment 2.Specific IgE/IgG4 antibody, cytokines, lymphocytes subsets 3.Prick test 4.Compliance of kakkonto 5.Induced reactions during the maintenance	—

Countries

Japan

Contacts

Public ContactYasunori Ito

Toyama University Hospital Pediatrics

yaitto-tym@umin.net81.76.434.2281

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026