Multicenter prospective study in acute pancreatitis

Multicenter prospective study in acute pancreatitis - SANADA(multicenter proSpective cohort in pAtieNts with severe And milD Acute pancreatitis) study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000025468

Enrollment

2000

Registered

2016-12-30

Start date

2017-01-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

acute pancreatitis

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: The patients who are diagnosed with acute pancreatitis will be included. The definition of acute pancreatitis requires 2 of the following 3 features: 1.upper abdominal pain of acute onset often radiating through to the back, 2.serum amylase or lipase activity greater than 3 times the upper limit of normal, 3.findings on cross sectional abdominal imaging consistent with acute pancreatitis.

Exclusion criteria

Exclusion criteria: None

Design outcomes

Primary

Measure	Time frame
Hospital mortality	—

Secondary

Measure	Time frame
Mortality within 14 days Mortality associated with pancreatitis Mortality after discharge at 1 year, 2years, 3years, 4years and 5 years and 5 years from admission Proportion which mild acute pancreatitis became severe acute pancreatitis based on the criteria of the Japanese Ministry of Health, Labour and Welfare study group for acute pancreatitis severity (2008)within 7 days The Rivised Atlanta classification within 7 days Transient(<=48h) and persistent(>48h) organ failure by Modified Marshall scoring system(respiratory, renal and cardiovascular)within 7 days Cotton classification Repiratory failure which need ventilator Renal failure which need dialysis Cardiovascular failure which need catecholamine Secondary infection in pancreatic necrosis Bacteremia Candida infection Modified CTSI(during 1 week to 4 weeks and, 4 weeks to 12 weeks, from occur) Walled-off necrosis(during 1 week to 4 weeks and, 4 weeks to 12 weeks, from occur) Surgical intervention(percutaneous, endoscopic, laparoscopic or laparotomy drainage or necrosectomy for infected acute necrotic collection or walled-off necrosis, interventional radiology or endoscopic treatment for bleeding,surgery for bowel necrosis or abdominal compartment syndrome Abdominal compartment syndrome, ECMO or IABP etc) Length of hospital and ICU stay The proportion of patients who discharge to home Disturbance in endocrine functionat(DM or inslin use) at discharge, 1 year, 2years, 3years, 4years and 5 years from admission Disturbance in exocrine functionat at discharge, 1 year, 2years, 3years, 4years and 5 years from admission The rate of chronic pancreatitis The rate of cancer The rate of pancreatitis recurrence The rate of multiple-drug-resistant bacteria Maximum of CRP value Decline rate of TG QOL(EQ-5D-5L) Cost QALY	—

Measure

Time frame

Mortality within 14 days Mortality associated with pancreatitis Mortality after discharge at 1 year, 2years, 3years, 4years and 5 years and 5 years from admission Proportion which mild acute pancreatitis became severe acute pancreatitis based on the criteria of the Japanese Ministry of Health, Labour and Welfare study group for acute pancreatitis severity (2008)within 7 days The Rivised Atlanta classification within 7 days Transient(<=48h) and persistent(>48h) organ failure by Modified Marshall scoring system(respiratory, renal and cardiovascular)within 7 days Cotton classification Repiratory failure which need ventilator Renal failure which need dialysis Cardiovascular failure which need catecholamine Secondary infection in pancreatic necrosis Bacteremia Candida infection Modified CTSI(during 1 week to 4 weeks and, 4 weeks to 12 weeks, from occur) Walled-off necrosis(during 1 week to 4 weeks and, 4 weeks to 12 weeks, from occur) Surgical intervention(percutaneous, endoscopic, laparoscopic or laparotomy drainage or necrosectomy for infected acute necrotic collection or walled-off necrosis, interventional radiology or endoscopic treatment for bleeding,surgery for bowel necrosis or abdominal compartment syndrome Abdominal compartment syndrome, ECMO or IABP etc) Length of hospital and ICU stay The proportion of patients who discharge to home Disturbance in endocrine functionat(DM or inslin use) at discharge, 1 year, 2years, 3years, 4years and 5 years from admission Disturbance in exocrine functionat at discharge, 1 year, 2years, 3years, 4years and 5 years from admission The rate of chronic pancreatitis The rate of cancer The rate of pancreatitis recurrence The rate of multiple-drug-resistant bacteria Maximum of CRP value Decline rate of TG QOL(EQ-5D-5L) Cost QALY

—

Countries

Japan

Contacts

Public ContactMasayasu Horibe

Keio University School of Medicine Division of Gastroenterology and Hepatology Department of Internal Medicine

masayasu-horibe@umin.ac.jp+81-3-5363-3790

Outcome results