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Optimization of Gadobutrol injection protocol for contrast-enhanced MR angiography in abdomen-lower extremity. ~Investigation in healthy volunteers~

Optimization of Gadobutrol injection protocol for contrast-enhanced MR angiography in abdomen-lower extremity. ~Investigation in healthy volunteers~ - Gadobutrol MRA of abdomen-lower extremity in healthy volunteers

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000025440
Enrollment
40
Registered
2017-01-11
Start date
2017-01-11
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Peripheral arterial obstruction diseases

Interventions

Gadobutrol is injected at a rate of 2ml/sec as for abdominal MRA, and 1ml/sec as for lower extremity MRA. Gadobutrol injection dose is decided 0.1ml/kg(Gadobutrol recomended dose in Japan). A half o

Sponsors

Hamamatsu Univercity school of medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Male and Female obtained written informed consent, not less than thirty years old.

Exclusion criteria

Exclusion criteria: 1.People who have past history of cardiovascular or arterial disease. 2.Woman who is pregnant,may be pregnant,or is breastfeeding. 3.People who had allergic history of contrast enhanced media. 4.People who can not take MRI(for example,people who have claustrophobia,devices which is unsupported for MRI,etc) 5.People who is judged inadequate by researchers.

Design outcomes

Primary

MeasureTime frame
Signal-to-noise-ratio and contrast-noise-ratio of Abdominal aorta, bilateral renal artery, iliac artery, femoral artery, popliteal artery, peroneal artery, anterior and posterior tibial artery.

Secondary

MeasureTime frame
1.Assessment of visualization in each artery 2.Presence of artifact 3.Presence of vein contamination 4.Assessment of intra- and inter-obserber agreement

Countries

Japan

Contacts

Public ContactTakasuke Ushio

Hamamatsu Univercity school of medicine Department of diagnostic radiology and nuclear medicine

tushio@hama-med.ac.jp053-435-2242

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026