A study for the effects of ingestion of food in adults with higher oxidative stress level and lower antioxidant ability : A randomized, double-blind, placebo controlled trial

A study for the effects of ingestion of food in adults with higher oxidative stress level and lower antioxidant ability : A randomized, double-blind, placebo controlled trial - A study for the effects of ingestion of food in adults with higher oxidative stress level and lower antioxidant ability

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000025373

Enrollment

Registered

2016-12-23

Start date

2016-12-24

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Adults with higher oxidative stress level and lower antioxidant ability

Interventions

Food containing a plurality of components, twice a day for 8 weeks Placebo without a plurality of components, twice a day for 8 weeks

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1) Men and women aged from 40 to 65 (2) higher oxidative stress level and lower antioxidant ability

Exclusion criteria

Exclusion criteria: (1)Subjects who regularly visit to ophthalmologic hospital for serious eye disease (2)Subjects who answered that there was a history of strength myopia in questionnaire (3)Subjects who received ophthalmic surgery within 3 months (4)Subjects who have a disease affecting the study results (e.g., cancer, hypertension, diabetes, amblyopia, autoimmune disease, thyroid dysfunction) (5) Subjects who have been taking foods affecting the study results once a week or more in the past month or expected to use once a week or more during study (6) Subjects who may have allergy to the test foods (7) Subjects who have a disease requiring regular medication or a history of serious diseases for which medication was required (8) Subjects who are judged as unsuitable for the study based on the results of clinical and physical examination on preliminary examination (9) Subjects who have participated in other clinical study within the last one month prior to the current study (10) Subjects who are planned to become pregnant after informed consent for the current study or are pregnant or lactating (11) Subjects who are judged as unsuitable for the study based on the results of lifestyle questionnaire (12) Subjects who are judged as unsuitable by doctor for other reasons

Design outcomes

Primary

Measure	Time frame
BAP Evaluate at points of 4-week and 8-week	—

Secondary

Measure	Time frame
d-ROMs, 8-OHdG, BAP/d-ROMs, Oxidative stress level, Endothelin, NO, visual acuity, ocular tension	—

Countries

Japan

Contacts

Public ContactHiroyasu Shimada

TTC Co., Ltd. Clinical Research Planning Department

h.shimada@ttc-tokyo.co.jp03-5459-5329

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026