Healthy adult
Conditions
Interventions
A drink: The polyphenol drink containing an oxidization component. B drink: The polyphenol drink which reduced the oxidization component by X treatment. C drink: The polyphenol drink which reduced t
Sponsors
Kao Coporation
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: 1) Subjects whose fasting blood glucose levels are ranged to less than 126mg/dL 2) Subjects whose HbA1c1 levels are ranged to less than 6.2% 3) Subjects whose BMI are from 18.5 Kg/m2 to less than 35 Kg/m2 4) Subjects who can make self-judgment and are voluntarily giving written informed consent
Exclusion criteria
Exclusion criteria: 1) Subjects who take continuous medical treatment 2) Subjects who are contracting heart disease, liver disease, kidney disease, digestive disease and allergy disease 3) Subjects with smoking habit 4) Subjects who are not eligible due to physician's judgment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood samples were collected before ingestion and at 0.5,1 and 2 hours after ingestion. FMD was measured before and 1, 2 and 4 hours after ingestion. Urine samples were collected before ingestion and accumulation urine samples were pooled during the postprandial periods for 2 and 4 hrs. Primary outcomes are oxidative stress markers and vascular endothelial function. | — |
Secondary
| Measure | Time frame |
|---|---|
| Key secondary outcomes are blood glucose. | — |
Countries
Japan
Contacts
Public ContactHiroko Jokura
Kao Coporation R&B-Core Technology-Biological Science Research
Outcome results
None listed