The healthy volunteers with pre-diabetes
Conditions
Interventions
Yamabuki Nadeshiko, a fermented green tea, 3g/day (1g/time) for 12 weeks
Placebo tea 3g/day (1g/time) for 12 weeks
Sponsors
University of Shizuoka
Shizuoka General Hospital SBS Shizuoka Health Promotion Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Fasting blood glucose levels from 100 mg/dL to 126 mg/dL Blood glucose levels from 140 mg/dL to 200 mg/gL after two-hour 75-gram oral glucose tolerance test
Exclusion criteria
Exclusion criteria: 1) HbA1c (NGSP) under 6.5% 2) Treatment for heart failure, myocardial infarction, malignant neoplasm, and the other diseases 3) Chronic diseases such as atrial fibrillation, arrhythmia, hepatopathy, nephropathy, cerebrovascular disease, rheumatism, diabetes, dyslipidemia, hypertension, and the others 4) Pregnancy, nursing, or a wish of pregnancy within next 6 months 5) The person who participates in other clinical trials at the time of this study entry 6) Smoker 7) Taking drugs, hyighly concentrated catechin-containing beverages, and a new supplement of effective for affecting blood glucose level 8) No agreement by documents 9) etc
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| fasting blood glucose level HbA1c (NGSP) A glucose tolerance test | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Insulin, HOMA-IR, Glico albumin 2.Blood Adiponectin level 3.Blood pressure 4.Blood and physical test 5.Cytokines and biological markers for diabetes and cardiovascular diseases | — |
Countries
Japan
Contacts
Public ContactTatsuya Morimoto
University of Shizuoka Division of Molecular Medicine, School of Pharmaceutical Sciences
Outcome results
None listed