Efficacy and safety of proton beam therapy in patients with previously untreated hepatocellular carcinoma

Efficacy and safety of proton beam therapy in patients with previously untreated hepatocellular carcinoma - Proton beam therapy for hepatocellular carcinoma

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000025342

Enrollment

129

Registered

2016-12-20

Start date

2002-01-13

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hepatocellular carcinoma

Interventions

Proton beam therapy 66 -77 GyE /10 - 35 fractions (days)

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Previously untreated hepatocellular carcinoma ECOG-PS: 0-2 Child-Pugh grade: A or B Non-irradiated normal liver volume: >= 500ml The tumor could be covered within the same irradiation field <= 135mm

Exclusion criteria

Exclusion criteria: massive ascites

Design outcomes

Primary

Measure	Time frame
overall survival	—

Secondary

Measure	Time frame
local tumor control rate, progression free survival, adverse events	—

Countries

Japan

Contacts

Public ContactKuniaki Fukuda

University of Tsukuba Gastroenterology

k-fukuda@md.tsukuba.ac.jp+81-29-853-3218

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026