Healthy adults
Conditions
Interventions
1. Single-dose study Duration: 1 day Test materials: Placebo tablets Administration: After a fasting blood and urine collection, 8 placebo tablets were ingested then take a rich in purine-containin
Sponsors
SAPPORO HOLDINGS LTD.
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Healthy Japanese adults of over 20 years old 2. Serum uric acid level was more than 5.0 mg/dL-8.0 mg/dL without gout symptoms 3. Those who received a full explanation of the procedures in the study, and informed consent was documented and signed by all of the participants
Exclusion criteria
Exclusion criteria: 1. Those who are receiving medication and/or treatment such as hyperuricemia, hypertension, diabetes mellitus etc. 2. Those who are allergic to citrus fruits 3. Those who are pregnant, breast-feeding, or are expected to become pregnant during the test period 4. Those who are going to have surgery and/or hospitalization within 2 months before and after the study period of Nov. 2016 to May 2017 5. Others consider as inappropriate for this test by the physician
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Serum uric acid level | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Blood biochemistry examination AST (GOT), ALT (GPT), gamma-GT (gamma-GTP), LDL-cholesterol, triglyceride (TG), and creatinine 2. Urinalysis Uric acid and creatinine | — |
Countries
Japan
Contacts
Public ContactKazuhiko YOSHIKAWA
SAPPORO HOLDINGS LTD. Group Research and Development Division
Outcome results
None listed