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The Clinical Comparison of Antidiabetic Agents Treating Postprandial Hyperglycemia, between Repaglinide alone and Mitiglide/Voglibose Fixed-dose Combination using Continuous Glucose Monitoring on Postprandial Profiles.

The Clinical Comparison of Antidiabetic Agents Treating Postprandial Hyperglycemia, between Repaglinide alone and Mitiglide/Voglibose Fixed-dose Combination using Continuous Glucose Monitoring on Postprandial Profiles. - The comparison between glinides and glinides/aGI combination therapy using CGM

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000025235
Enrollment
30
Registered
2016-12-12
Start date
2016-12-06
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 diabetes

Interventions

Glycemic levels were monitored for 7 consecutive days using CGM (ipro2
Medtronic MiniMed Inc., Northridge, CA).During the study period, the dose ofinsulin and other antidiabetic drugs were fixed.The patients were divided three arms. After starting glucose monitoring,

Sponsors

Dokkyo Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1)Type 2 diabetes in patient 2)Postprandial glucose levels > 180mg/dl 3)HbA1c values at admition between 7.0 and 13.5% 4)Patients who gave written informed consent

Exclusion criteria

Exclusion criteria: 1)Patients who have severe diabeticketosis, diabetic coma 2)Patients with severe infections, severe injury or perioperative state. 3)Female patients who have pregnancy or possibilty of pregnancy, or are under lactation 4)Patients who had past history of hypersensitivity or allergic reaction to insulin degludec, aspart or liraglutide 5)Patients with severe liver or renal dysfunction.

Design outcomes

Primary

MeasureTime frame
Total area under the curve (AUC) within 2 h after each meal, and postprandial glucose levels within 2 h after each meals using 24-h glycemic data from CGM

Secondary

MeasureTime frame
we evaluated 24-h mean glucose levels,the mean of the daily difference, mean amplitude of glycemic excursions,rates of proportions of appropriate glucose levels, hyperglycemia, andhypoglycemia

Countries

Japan

Contacts

Public ContactTakafumi Niitani

Dokkyo Medical University Endocrinology and Metabolism

niinii@dokkyomed.ac.jp0282-86-1111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026