Analysis of human DNA metylation in patients with digestive organ cancer

Analysis of human DNA metylation in patients with digestive organ cancer - DNA metylation of DOC

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000025230

Enrollment

1300

Registered

2017-01-01

Start date

2017-01-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Digestive organ diseases including digestive otrgan cancers

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients with digestive organ cancers (1) Patients who are clinically diagnosed as digestive organ cancer (colorectal cancer, gastric cancer, pancreatic cancer, or liver cancer) (2) Age >= 20 years; male and female (3) Inpatient and outpatient (4) Patients from whom informed consent is obtained 2. Patients with benign digestive organ diseases (1) Patients who are diagnosed as benign digestive organ disease (colorectal adnoma, inflammatory bowel disease, gastric adenoma, gastric ulcer, chronic pancreatitis, or chronic liver disease) (2) Age >= 20 years; male and female (3) No objection to previous cancer with healed state (4) Inpatient and outpatient (5) Patients from whom informed consent is obtained 3. Healty subject (1) Age >= 20 years; male and female (2) NO digestive symptoms and no wight loss (3) Parson who has a medical checkup result wihin 1 year (4) Parson who has no abnormalities in a medical checkup result within 1 year

Exclusion criteria

Exclusion criteria: 1. Patients with digestive organ cancers (1) Patients with double cancer (2) Patients who are judged as inadequacy due to other reasons 2. Patients with benign digestive organ diseases (1) Patients who are judged as inadequacy due to other reasons 3. Healty subject (1) Person with diabetes mellitus (2) Person with previous cancer (3) Person with previous colorectal disease (4) Person with previous gastric disease (5) Person with previous pancreatic disease (6) Person with previous liver disease (7) Person who is judged as inadequacy

Design outcomes

Primary

Measure	Time frame
Detection rate of DNA metylation on each digestive organ cancers	—

Secondary

Measure	Time frame
1. Comparison between DNA metylation and histological finding 2. DNA metylation and prognosis	—

Countries

Japan

Contacts

Public ContactTakahiro Yamasaki

Yamaguchi University Graduate School of Medicine Department of Oncology and Laboratory Medicine

rinken@yamaguchi-u.ac.jp0836-22-2337

Outcome results