A prospective genetic study of patients with bilateral Wilms tumor for preparation of genetic counseling (RTBL14GP2)

A prospective genetic study of patients with bilateral Wilms tumor for preparation of genetic counseling (RTBL14GP2) - A genetic study of bilateral Wilms tumor

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000025155

Enrollment

Registered

2016-12-06

Start date

2014-06-05

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bilateral Wilms tumor

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Registered patients to Multi-center clinical trial for Japanese children with bilateral nephroblastoma (RTBL14)

Exclusion criteria

Exclusion criteria: Patients not to register to Multi-center clinical trial for Japanese children with bilateral nephroblastoma (RTBL14)

Design outcomes

Primary

Measure	Time frame
To identify various germinal mutations and the incidence of each germinal mutation, that caused bilateral Wilms tumor.	—

Secondary

Measure	Time frame
1) To clarify that the germinal mutations identified in patients with bilateral Wilms tumor are inherited from their parents or occurred de novo. 2) To identify germinal mutations in blood from families and to clarify the association between the mutation and their past history of Wilms tumor in order to determine the penetrance rates of bilateral Wilms tumor.	—

Countries

Japan

Contacts

Public ContactMasayuki Haruta

Research Institute for Clinical Oncology, Saitama Cancer Center Cancer Diagnosis

haruta@cancer-c.pref.saitama.jp048-722-1111

Outcome results