Development of the hepato-biliary-pancreatic tumor-specific imaging technique on targeting amino acid transporter

Development of the hepato-biliary-pancreatic tumor-specific imaging technique on targeting amino acid transporter - Development of the novel tumor-specific imaging technique

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000025110

Enrollment

Registered

2017-01-01

Start date

2017-01-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hepatocellular carcinoma,biliary tract cancer,pancreatic cancer

Interventions

[18F]AA-7 [18F]FDG

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients 1) with hepato-biliary-pancreatic tumor in Osaka City University Hospital, who give informed consent. Diagnostic criteria Hepatocellular carcinoma: imaging (ultrasonography, CT, MRI, angiography), tumor marker (AFP, PIVKA-2), pathological diagnosis Biliary and pancreatic tumor: imaging (ultrasonography, CT, MRI, angiography, ERCP) , tumor marker (CEA, CA19-9, SPAN-1, DUPAN-2), pathological diagnosis 2) who is between 20 and 80 years old (regardless of sex) 3) who give informed consent 4) who can be hospitalized before examination for controlling blood sugar and amino acid levels 5) who can survive more than six months 6) who can reach the ECOG score 0 or 1

Exclusion criteria

Exclusion criteria: Patients 1) with serious brain and/or kidney disease 2) with a history of chemotherapy 3) with pregnancy women 4) with claustrophobia 5) with grade C of Child-Pugh score (Hepatocellular carcinoma) 6) who are judged as not suitable for participation in this study

Design outcomes

Primary

Measure	Time frame
Intratumoral accumulation and distribution of the PET probe ([18F]AA-7 and [18F]FDG) before and after treatment	—

Countries

Japan

Contacts

Public ContactSatoshi Nozaki

Osaka City University Graduate School of Medicine Department of Physiology

satoshi.nozaki@riken.jp06-6645-3711

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026